People with heart disease should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Infections: Corticosteroids can reduce your body's ability to fight infections and may hide signs of infection that is developing. If you have had tuberculosis in the past, methylprednisolone may cause the infection to return. If you experience signs of infection such as sore throat, fever, sneezing, or coughing, contact your doctor as soon as possible. Kidney disease: Methylprednisolone may not clear from the body at the expected rate in cases where the kidney is not working properly.
If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Liver function: Methylprednisolone may not clear from the body at the expected rate in cases where the liver is not working properly. If you have reduced liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Methylprednisolone may also cause harm to the liver. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Myasthenia gravis: Myasthenia gravis is a condition that causes specific muscle weakness. Methylprednisolone can cause muscle wasting or decreasing muscle. If you have myasthenia gravis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Ocular herpes simplex: People who have the herpes simplex virus affecting their eye should be monitored by their doctor while taking methylprednisolone, as the medication may cause damage to the cornea. Osteoporosis bone disease : Methylprednisolone causes the body to lose calcium and may cause osteoporosis to develop or worsen.
If you have osteoporosis or are at risk of developing osteoporosis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Pancreatitis: Corticosteroids can cause the pancreas to become inflamed. Report signs of pancreatitis such as abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, or swollen abdomen to your doctor immediately.
Skin test injection: Methylprednisolone, like other corticosteroids, can cause false negative test results i. Stomach ulcer: Methylprednisolone may cause stomach ulcers to worsen or develop. If you have stomach problems or a history of stomach problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Stress: A dosage adjustment of methylprednisolone may be required for anyone subjected to unusual stress.
Underactive thyroid hypothyroidism : Methylprednisolone may not clear from the body at the expected rate when a person is hypothyroid. As a result, the effects of the medication may be increased. If you have hypothyroidism, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Vaccines: People receiving immunosuppressive doses of corticosteroids should not receive live or live-attenuated modified vaccines, as there is a risk of infection and poor immune response to the vaccine. Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. Note: If a drug has been approved for one use, physicians sometimes elect to use this same drug for other problems if they believe it might be helpful. This list includes common and less common side effects for individuals taking Medrol. However, you should always inform your health care provider if you experience any unusual symptoms. Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:.
The following symptoms require medical attention, but are not emergency situations. Contact your health care provider within 24 hours of noticing any of the following:. You will be checked regularly by your health care professional while you are taking Medrol, to monitor side effects and check your response to therapy. Periodic blood work to monitor your complete blood count CBC as well as the function of other organs such as your kidneys and liver will also be ordered by your doctor.
It is best to speak with your healthcare provider before starting any new medications. When taken with Medrol, the following can increase the risk of side effects due to increased concentrations of methylprednisolone in the body:. Medrol can also cause an increased risk of side effects from other medications such as:.
The following medications may cause Medrol to be less effective:. This list does not include all drugs that can interact with methylprednisolone. Before taking methylprednisolone, be sure to tell your doctor about all of the prescription medications, over-the-counter medications, vitamins, supplements, and herbs you are taking. This will help you avoid potential interactions.
If you have any questions about drug interactions, speak with your doctor or pharmacist. Medrol is part of a class of medications known as glucocorticoids. Other commonly prescribed glucocorticoids include:. Dexamethasone is available as an oral tablet. It is often prescribed to treat inflammation, allergic reactions, adrenal insufficiency, and flare-ups of ulcerative colitis. The most common side effects include stomach upset, swelling, high blood glucose, and trouble falling asleep.
Dexamethasone is also available as an oral solution, eye drops, and ear drops. Prednisone is available as an oral tablet. It helps reduce inflammation, irritation, or swelling, and treats many conditions such as rheumatoid arthritis and dermatitis. Common side effects include restlessness, acne, nausea or vomiting, trouble sleeping, and weight gain. Prednisone is also available as a liquid solution. Hydrocortisone is available as an oral tablet.
It is often prescribed to treat adrenocortical deficiency, swelling, and inflammation, and is used to slow down your immune system. Common side effects include headaches, muscle weakness, and skin problems.
Hydrocortisone is also available as an injection and topical form. This is a list of drugs from similar classes of medication as Medrol.
It is not a list of drugs recommended to take with Medrol. Ask your pharmacist or healthcare provider if you have any questions. It works by decreasing inflammation in the body.
Medrol is often used to treat various disorders such as rheumatoid arthritis, lupus, psoriasis, Stevens-Johnson syndrome, and ulcerative colitis. The most common side effects are weight gain, nausea or vomiting, increased thirst, and headache. Methylprednisolone also has the potential for serious side effects such as an allergic reaction, changes in mood, low potassium levels, or diabetes.
Abruptly stopping Medrol may lead to side effects. You could also have flare-ups of your disease, or your pain and inflammation symptoms could recur.
It is best to speak with your healthcare provider before you stop taking this medication. Medrol is a safe and effective medication when used correctly. While Medrol does have the potential for serious side effects such as allergic reactions, changes in mood, or dangerously low potassium levels, the most common side effects tend to be mild.
Those might include headache, nausea, vomiting, weight gain, or increased thirst. It is important to inform your healthcare provider of your other medical conditions and any prescription medications, OTC medications, vitamins, supplements, and herbs you are taking.
This way, your provider can make the best decision about what medication and dose are safe and will work best for you.
Verywell Health's drug information is meant for education purposes only and not intended as a replacement for medical advice, diagnosis, or treatment from a healthcare professional. Consult your doctor before taking any new medication s.
IBM Watson Micromedex provides some of the drug content, as indicated on the page. Dealing with chronic inflammation? An anti-inflammatory diet can help. Our free recipe guide shows you the best foods to fight inflammation. Get yours today! National Library of Medicine, DailyMed. Make sure any doctor caring for you knows you are using this medicine.
Call your doctor for instructions if you miss an appointment for your methylprednisolone injection. Methylprednisolone works quickly. It reaches its peak effect within about one hour after an intravenous dose. Its peak effect is about two hours when given orally. Let your provider know if you experience any unusual side effects after receiving this medicine. Methylprednisolone is prescribed for many different health problems.
Health Topics. Health Tools. Methylprednisolone Medrol. Reviewed: January 18, Tell your doctor if you have ever had: heart disease, high blood pressure; a thyroid disorder; diabetes; glaucoma or cataracts; kidney disease; cirrhosis or other liver disease; seizures, epilepsy or recent head injury; past or present tuberculosis; herpes infection of the eyes; a condition called scleroderma; stomach ulcers, ulcerative colitis, diverticulitis, or recent intestinal surgery; a parasite infection that causes diarrhea such as threadworms ; mental illness or psychosis; osteoporosis or low bone mineral density steroid medication can increase your risk of bone loss ; a muscle disorder such as myasthenia gravis; or an electrolyte imbalance such as low levels of potassium in your blood.
You should not breast-feed while using methylprednisolone. Side Effects.
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